Updates in Cognition and Multiple Sclerosis

Posttest

Updates in Cognition and Multiple Sclerosis:
Expert Guidance on Management Across the Continuum of the Disease

Please choose the best answer for the questions below, then click the button at the bottom to proceed.

Items marked with * require a response.
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1. Which of the following best describes cognitive symptoms in people with multiple sclerosis (PwMS)?*
- The cognitive domains most frequently affected include information processing speed and executive function
- There are 4 distinct cognitive phenotypes, distinguished by domains affected
- The prevalence of cognitive impairment is greater in older patients and rarely occurs in children and teenagers
- No gender-based differences in the nature or prevalence of cognitive impairment have been observed in clinical trials
2. Which of the following MRI findings is the strongest known predictor of cognitive decline in PwMS?*
- Lesion number
- Lesion volume
- Whole brain atrophy
- Regional brain matter loss
3. Which of the following best summarizes evidence related to the effects of disease-modifying therapies (DMTs) on MS-related cognitive impairment?*
- There is substantial evidence from observational studies demonstrating beneficial effects of DMTs on cognitive performance, but there are no data from randomized controlled trials (RCTs)
- Beneficial effects of DMTs on cognitive performance have been demonstrated in a few RCTs, but data are limited
- Several RCTs have demonstrated short-term improvements in cognitive performance, but improvements were not maintained over time
- In clinical trials, DMTs have been shown to slow cognitive decline, but improvements in cognitive performance have not been demonstrated
4. A 25-year-old woman presents to the neurology clinic as a new patient. She was recently diagnosed with clinically isolated syndrome (CIS) after experiencing an episode of acute optic neuritis. Which of the following approaches to cognitive assessment would be the most appropriate?*
- Ask the patient to complete a brief cognitive assessment using a screening tool
- Refer the patient to a neuropsychologist with expertise in MS for a full cognitive battery
- Ask a close family member or friend to complete a questionnaire about the patient’s cognition
- Plan to perform a cognitive assessment if the patient develops clinically definite MS

PosttestUpdates in Cognition and Multiple Sclerosis:Expert Guidance on Management Across the Continuum of the Disease

Posttest

Updates in Cognition and Multiple Sclerosis:
Expert Guidance on Management Across the Continuum of the Disease