Building Clinical Confidence

Module 4. Symptom management

Posttest

Please choose the best answer for all the questions below, then click the button at the bottom to proceed.

Items marked with * require a response.

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1. Which of the following is true about treatments for walking/gait in patients with MS?*

Intrathecal baclofen infusion is FDA-approved to improve walking in MS
In clinical trials, dalfampridine improved clinician-measured walking speed but not patient-reported symptoms
An adaptable, configurable functional electronic stimulation (FES) device is FDA-approved to aid with walking in patients with foot drop
The antiepileptic drugs gabapentin and pregabalin are considered first-line therapy for walking difficulties

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2. Which of the following treatment options for spasticity can be administered in low doses directly to the spinal cord?*

Tizanidine
Baclofen
Gabapentin
Dantrolene

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3. Which of the following is (are) most consistently associated with decreased MS-related pain levels in clinical trials?*

Electrical stimulation near site of limb pain
Mindfulness-based interventions
Clonazepam
Monoamine oxidase inhibitors

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4. Which of the following is associated with relief of fatigue in patients with MS in clinical trials?*

Transcranial direct current stimulation
Methylphenidate
Botulinum toxin injections
Heat therapy

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5. Which of the following is associated with improved cognitive processing speed in patients with MS in randomized controlled clinical trials?*

Compensatory strategies, such as mental imagery
Donepezil
Memantine
Siponimod

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6. Which of the following is considered first-line treatment for patients with MS and overactive bladder?*

Alpha-1 adrenergic blockers
Antimuscarinics
Mirabegron
Percutaneous tibial nerve stimulation

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7. Which of the following describes the role of exercise in the management of MS symptoms?*

Recommended for all patients with MS
Recommended only for patients with Expanded Disability Status Scale (EDSS) scores of 6 or less
Aerobic exercise is more effective than yoga in improving mobility and reducing fatigue
Exercise is associated with symptomatic improvement only, without structural or functional brain changes

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8. Which of the following statements regarding the gut microbiome and probiotic intake in people with MS is true?*

Probiotics are associated with improved disease severity and mental health in patients with MS
Probiotics increase brain and gut neuroinflammation
Microbial products impact gut neural network activity but do not affect the central nervous system (CNS)
There is no significant difference in bacterial composition of the gut biome in the MS and non-MS populations

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9. Placebo-controlled trials have found that which of the following is associated with less fatigue and improved quality of life in patients with MS?*

St John’s wort
Chamomile
Ginseng
Tea tree oil

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10. For which of the following integrative medicine approaches is there the strongest evidence of beneficial effects on MS-related symptoms?*

Therapeutic touch
Rolfing
Cupping
Acupuncture

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