Rationale for Correct Answer
The correct answer is: Recommended for all patients with MS
Exercise is recommended for all patients with MS.1 A variety of exercises provide symptomatic benefits, including endurance training, muscle-power training, task-oriented training, mixed programs, and yoga.2 Symptomatic benefits include improved mobility, muscle power, mood, memory, walking speed, balance, and QOL,2,3 as well as less fatigue. Exercise is also associated with structural and functional brain changes: reduced neural apoptosis, neurodegeneration, and markers of blood-brain barrier (BBB) permeability; increased cortical thickening and functional connectivities.3-5
References:
1. Kalb R et al. Mult. Scler. 2020, 26:1459-1469.
2. Amatya B et al. Cochrane Database Syst Rev. 2019;1:CD012732.
3. Negaresh R et al. Eur J Neurol. 2019;26:711-721.
4. Learmonth YC, et al. Int J Environ Res Public Health. 2021;18:13245.
5. Kjølhede T et al. Mult Scler. 2018;24:1356-1365.